Early in the illness, patients usually experience psychiatric
symptoms, which most commonly take the form of depression or, less often, a
schizophrenia-like psychosis. Unusual sensory symptoms, such as "stickiness" of
the skin, have been experienced by half of the cases early in the illness.
Neurological signs, including unsteadiness, difficulty walking and involuntary
movements, develop as the illness progresses and, by the time of death, patients
become completely immobile and