
| Protein requirements of infants and children |
The procedures for making adjustments for protein digestibility and quality were described thoroughly in the 1985 report and in a subsequent Joint FAO/WHO expert report (Joint FAO/WHO Expert Consultation on Protein Quality Evaluation, 1991) and do not need to be reiterated here. Use of the protein digestibility corrected amino acid score is considered the most appropriate method for evaluating protein quality. This method obviously depends heavily on the estimated amino acid requirements at each age. For infants, both the 1985 report and the 1991 Consultation recommended that the amino acid composition of human milk be accepted as the suggested pattern of requirement. However, as the discussion in section 2.5 indicates, the essential amino acid content of human milk is generally above 'requirements' based on calculated needs for growth and maintenance. Thus, using the human milk amino acid pattern (mg/g protein) as the basis for evaluating weaning foods may underestimate their protein quality (depending on which amino acids are potentially limiting in the food being evaluated).
For children, the 1991 Consultation (FAO/WHO Expert Consultation, 1991) recommended that the amino acid scoring pattern for preschool children (see section 3.4) be used for all age groups (except infants). Until more information is available on amino acid requirements, this recommendation appears to be justified. However, because that scoring pattern was based on only one set of studies in a small sample of children, replication of the findings is essential. The lack of information on sulfur amino acid needs is particularly unfortunate as these amino acids, together with Lysine, may be marginal in vegetable protein sources if Rose's (1957) 'safe' rather than 'minimal' level is closer to true needs (see section 2.5). Even so, data from Guatemala (Scrimshaw et al, 1961; Torun and Viteri, 1981b; Torun et al, 1984) suggest that predominantly vegetable multi mixes can provide an adequate source of amino acids for children beyond the age of one year.
Aside from protein quality, any evaluation of weaning foods must also consider the content and bioavailability of other nutrients, particularly trace elements, and the potential presence of 'antinutritional' factors such as plant lectins.