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close this bookProtein-Energy Interactions (International Dietary Energy Consultative Group - IDECG, 1991, 437 pages)
close this folderResearch needs
close this folder2. Protein metabolism and requirements
View the document2.1. Amino acid oxidation
View the document2.2. Amino acid requirements
View the document2.3. Protein requirements during pregnancy and lactation
View the document2.4. Control of urea recycling from the gut
View the document2.5. Limits to the de novo synthesis of 'conditionally essential' amino acids
View the document2.6. Special roles of particular amino acids

2.5. Limits to the de novo synthesis of 'conditionally essential' amino acids

It is increasingly recognized that some amino acids, classically described as 'dispersible' or 'non-essential', may become limiting under conditions of high demand, such as rapid growth or in response to injury. Amino acids in this category are glycine, serine, proline, possibly arginine and cysteine. Collagen in particular, but also the acute phase proteins, contain disproportionately large amounts of these amino acids. It is therefore important to have more information on the rates of de novo synthesis that can be achieved under different conditions, and on factors that may affect those rates.