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close this bookProtein-Energy Interactions (IDECG, 1991, 437 p.)
close this folderExercise, aging and protein metabolism
View the document(introduction...)
View the document1. Body composition changes with age and their consequences
View the document2. Fuels used to meet various components of energy requirements
View the document3. Age and dietary protein needs
View the document4. Exercise-induced muscle damage and acute phase response
View the document5. Exercise and protein metabolism
View the document6. Summary
View the documentReferences

References

ANIANSSON, A., ZETTERBERG, C., HEDBERG, B., KOMI, P.V.: Impaired muscle function with aging. A background factor in the incidence of fractures of the proximal end of the femur. Clin. Orth. Rel. Res., 191, 193-200 (1984).

ASMUSSEN, E.: Observations on experimental muscular soreness. Acta Rhum. Scand., 2, 109-116 (1956).

BABIOR, B.M., KIPNES, R.S., CURNUTTE, J.T.: The production by leukocytes of super-oxide, a potential bactericidal agent. J. Clin. Invest., 52, 741-744 (1973).

BAINTON, D.F.: Phagocytic cells: Developmental biology of neutrophils and eosinophils. In: Inflammation: Basic Principles and Clinical Correlates, pp. 265-280, J.I. GALLIN, I.M. GOLDSTEIN, R. SNYDERMAN (Eds.). Raven Press, New York, NY, 1988.

CAMPBELL, W.W., CRIM, M.C., JOSEPH, L.J., YOUNG, V.R., EVANS, W.J.: Protein turnover in young and older men related to fat free mass and muscle. FASEB J., 6, A1942 (1992)

CANNON, J.G., KLUGER, M.J.: Endogenous pyrogen activity in human plasma after exercise. Science, 220, 617-619 (1983).

CANNON, J.G., FIELDING, R.A., FIATARONE, M.A., ORENCOLE, S.F., DINARELLO, C.A. EVANS, W.J.: Interleukin-1b in human skeletal muscle following exercise. Am. J. Physiol., 257, R451-R455 (1989).

CANNON, J.G., ORENCOLE, S.F., FIELDING. R.A., MEYDANI, M., MEYDANI, S.N., FIATARONE, M.A., BLUMBERG, J.B., EVANS, W.J.: Acute phase response in exercise: interaction of age and vitamin E on neutrophils and muscle enzyme release. Am. J. Physiol., 259, R1214-R1219 (1990).

CANNON, J.G., MEYDANI, S.N., FIELDING, R.A., FIATARONE, M.A., MEYDANI, M., FARHANGMEHR, M., ORENCOLE, S.F., BLUMBERG, J.B., EVANS W.J.: Acute phase response in exercise. II. Associations between vitamin E, cytokines, and muscle proteolysis. Am. J. Physiol., 260, R1235-R1240 (1991).

CARRARO, E, STUART, C.A., HARTL, W.H., ROSENBLATT, J. WOLFE, R.R.: Effect of exercise and recovery on muscle protein synthesis in human subjects. Am. J. Physiol., 259, E470-E476 (1990).

CATHCART, E.P.: The influence of muscle work on protein metabolism. Physiol. Rev., 5, 225-243 (1925).

CIRIELLO, V.M., HOLDEN, W.L., EVANS, W.J.: The effects of two isokinetic training regimens on muscle strength and fiber composition. In: Biochemistry of Exercise, pp. 787 - 793, H.G. KNUTTGEN, J.A. VOGEL, J. POORTMANS (Eds.). Human Kinetics Publishers, Inc., Champaign, IL, 1983.

COHN, S.H., VARTSKY, D., YASUMURA, S., SAVITSKY, A., ZANZI, I., VASWANI, A., ELLIS, K.J.: Compartmental body composition based on total-body, potassium, and calcium. Am. J. Physiol., 239, E524-E530 (1980).

COLLIANDER, E.B., TESCH, P.A.: Effects of eccentric and concentric muscle actions in resistance training. Acta Physiol. Scand., 140, 31-39 (1990).

DEVLIN, J.T., BRODSKY, I., SCRIMGEOUR, A., FULLER, S., BIER, D.M. Amino acid metabolism after intense exercise. Am. J. Physiol., 258, E249-E255 (1990).

DUAN, C., DELP, M.D., HAYES, D.A., DELP, P.D., ARMSTRONG, R.B.: Rat skeletal muscle minochondrial [Ca2+] and injury from downhill walking. J. Appl. Physiol., 68, 1241-1251 (1990).

DUDELY, G.A., TESCH, P.A., MILLER, M.A., BUCHANAN, M.D.: Importance of eccentric actions in performance adaptations to resistance training. Aviat. Space Environ. Med., 62, 543-550 (1991).

EVANS, W.J.: Exercise and muscle metabolism in the elderly. In: Nutrition and Aging, pp. 170-191, M.L. HUTCHINSON, H.N. MUNRO (Eds.). Academic Press, San Diego, CA, 1986.

EVANS, W.J., FISHER, E.C., HOERR, R.A., YOUNG, V.R.: Protein metabolism and endurance exercise. Physic Sports Med., 11, 63-72 (1983).

EVANS, W.J., MEREDITH, C.N., CANNON, J.G., DINARELLO, D.A., FRONTERA, W.R., HUGHES, V.A., JONES, B.H., KNUTTGEN, H.G.: Metabolic changes following eccentric exercise in trained and untrained men. J. Appl. Physiol., 61, 1864-1868 (1986).

EVANS, W.J., MEREDITH, C.N.: Exercise and nutrition in the elderly. In: Nutrition, Aging, and the Elderly, pp. 89-126, H.N. MUNRO, D.E. DANFORD (Eds.). Plenum Press, New York, NY, 1989.

EVANS, W.J., ROSENBERG, I.R., THOMPSON, J.: Biomarkers: The Ten Determinants of Aging You Can Control. Simon & Schuster, New York, NY, 1991.

FIATARONE, M.A., EVANS, W.J.: Exercise in the oldest old. Top. Geriatr. Rehab., 5, 63-77 (1990).

FIATARONE, M.A., MARKS, E.C., RYAN, N.D., MEREDITH, C.N., LIPSITZ, L.A., EVANS, W.J. High-intensity strength training in nonagenarians. Effects on skeletal muscle. JAMA, 263, 3029-3034 (1990).

FICK, A., WISCLICENUS, J.: On the origin of muscular power. Philosophical Magazine and Journal of Science, 31, 485-503 (1866).

FIELDING, R.A., EVANS, W.J., HUGHES, V.A., MOLDAWER, L.L., BISTRIAN, B.R. The effects of high intensity exercise on muscle and plasma levels of alpha-ketoisocaproic acid. Eur. J. Appl. Physiol., 482-485 (1986).

FIELDING, R.A., MEREDITH, C.A., O'REILLY, K.P., FRONTERA, W.R., CANNON, J.G., EVANS, W.J.: Enhanced protein breakdown following eccentric exercise in young and old men. J. Appl. Physiol., 71, 674-679 (1991).

FINK, W.J., COSTILL, D.L., VAN HANDEL, W.J.: Leg muscle metabolism during exercise in the heat and cold. Eur. J. Appl. Physiol., 34, 183-190 (1975).

FISHER, E.C., NELSON, M.E., FFRONTERA, W.R., TURKSOY, R.N., EVANS, W.J: Bone mineral content and levels of gonadotropins and estrogens in amenorrheic running women. J. Clin. Endocrinol. Metab., 92, 1232-1236 (1986).

FRIDEN, J., SEGER, J., SJTR, M., EKBLOM, B.: Adaptive response in human skeletal muscle subjected to prolonged eccentric training. Int. J. Sports Med., 4, 177-183 (1983).

FRONTERA, W.R., EVANS, W.J.: Exercise performance and endurance training in the elderly. Top. Geriatr. Rehab., 2, 17-32 (1986).

FRONTERA, W.R., MEREDITH, C.N., O'REILLY, K.P., KNUTTGEN, H.G., EVANS, W.J.: Strength conditioning in older men: skeletal muscle hypertrophy and improved function. J. Appl. Physiol., 64, 1038-1044 (1988).

GERSOVITZ, M. BIER. D., MATTHEWS, D., UDALL, J., MUNRO, H., YOUNG, V.: Dynamic aspects of whole body glycine metabolism: influence of protein intake in young adult and elderly males. Metabolism, 29, 1087-1094 (1980).

GERSOVITZ, M., MUNRO, H., SCRIMSHAW, N., YOUNG, V.: Human protein requirements: assessment of the adequacy of the current recommended dietary allowance for dietary protein in elderly men and women. Am. J. Clin. Nutr., 35, 6-14 (1982).

GONTZEA, 1., SUTZESCU, P., DUMITRACHE, S.: The influence of muscle activity on nitrogen balance and the need of man for proteins. Nutr. Rep. Int., 10, 35-43 (1974).

GONTZEA, I., SUTZESCU, R., DUMITRACHE, S.: The influence of adaptation to physical effort on nitrogen balance in man. Nutr. Rep. Int., 11, 231-236 (1975).

HARALAMBIE, G., BERG, A.: Serum urea and amino nitrogen changes with exercise duration. Eur. J. Appl. Occup. Physiol., 36, 39-48 (1976).

HIKIDA, R.S., STARON, R.S., HAGERMAN, F.C., SHERMAN, W.M., COSTILL, D.L.: Muscle fiber necrosis associated with human marathon runners. J. Neurol. Sci., 59, 185-203 (1983).

HUGHES, V.A., FIATARONE, M.A., FIEDLING, R.A., KAHN, B.R., FERRA, C.M., SHEPHERD, R. FISHER, E.C., WOLFE, R.R., ELAHI, D., EVANS, W.J.: Aerobic exercise improves glucose homeostasis and increases GLUT 4 levels in skeletal muscle of older subjects with impaired glucose tolerance. Am. J. Physiol. In review.

IMAMURA, K., ASHIDA, H., ISHIKAWA, T., FUJII, M.: Human major psoas muscle and sacrospinalis muscle in relation to age: A study by computed tomography. J. Gerontol., 38, 678-681 (1983).

JOHNSTON, R.B.: Monocytes and macrophages. N. Engl. J. Med., 318, 747-752 (1988).

JONES, D.A., NEWHAM, D.J., ROUND, J.M., TOLFREE, S.E.J.: Experimental human muscle damage: morphological changes in relation to other indices of damage. J. Physiol. (London), 375, 435-448 (1986).

KAMPSCHMIDT, R.: Leukocytic endogenous mediator/endogenous pyrogen. In: Infection: the Physiologic and Metabolic Reponses of the Host, pp. 55-74, M.C. POWANDA, P.G. CANONICO (Eds.). Elsevier/North Holland, Amsterdam, 1981.

KLITGAARD, H., MANTONI, M., SCHIAFFINO, S., AUSONI, S., GORZA, L., LAURENT-WINTER, C., SCHNOHR, P., SALTIN, B.: Function, morphology and protein expression of ageing skeletal muscle: a cross-sectional study of elderly men with different training backgrounds. Acta Physiol. Scand., 140, 41-54 (1990a).

KLITGAARD, H. ZHOU, M., SCHIAFFINO, S., BETTO, R., SALVIATI, G., SALTIN, B.: Ageing alters the myosin heavy chain composition of single fibres from human skeletal muscle. Acta Physiol. Scand., 140, 55-62 (1990b).

KNAPIK, J., MEREDITH, C., JONES, B., FIELDING, R., YOUNG, V., EVANS, W.: Leucine metabolism during fasting and exercise. J. Appl. Physiol., 70, 43-47 (1991).

KOMI, P.V., BUSKIRK, E.B.: Effect of eccentric and concentric muscle conditioning on tension and eletrical activity of human muscle. Ergonomics, 15, 417-434 (1972).

LARSSON, L.: Histochemical characteristics of human skeletal muscle during aging. Acta Physiol. Scand., 117, 469-471(1983).

LEMON, P.W.R., MULLIN, J.: Effect of initial muscle glycogen levels on protein catabolism during exercise. J. Appl. Physiol., 48, 624-629 (1980).

LEMON, P.W.R., DOLNY, D.G., YARESHESKI, K.E.: Effect of intensity on protein utilization during prolonged exercise. Med. Sci. Sports Exerc., 16, 151 (1984).

LEXELL, J., HENRIKSSON-LARSEN, K., WIMBLOD, B., SJTR, M.: Distribution of different fiber types in human skeletal muscles: Effects of aging studied in whole muscle cross sections. Muscle Nerve, 6, 588-595 (1983).

MANFREDI, T.G., FIELDING. R.A., O'REILLY, K.P., MEREDITH, C.N., LEE, H.Y., EVANS, W.J.: Serum creating kinase activity and exercise-induced muscle damage in older men. Med. Sci. Sports Excerc., 23, 1028-1034 (1991).

MEREDITH, C.N., FRONTERA, W.R., FISHER, E.C., HERLAND, J.C., EDWARDS, J., EVANS, W.J.: Peripheral effects of endurance training in young and old subjects. J. Appl. Physiol., 66, 2844-2849 (1989a).

MEREDITH, C.N., ZACKIN, M.J., FRONTERA, W.R., EVANS, W.J.: Dietary protein requirements and body protein metabolism in endurance-trained men. J. Appl. Physiol., 66, 2850-2856 (1989b).

MEREDITH, C.N., FRONTERA, W.R., EVANS, W.J.: Body composition in elderly men. Effect of dietary modification during strength training. J. Am. Geriatr. Soc. (1992).

MILLWARD, D.J., DAVIES, C.T.M, HALLIDAY, D., WOLMAN, S.L., MATTHEWS, D., RENNIE, M.: Effect of exercise on protein metabolism in humans as explored with stable isotopes. Fed. Proc., 41, 2686-2691 (1982).

NAWABI, M.D., BLOCK, K.P., CHAKRABARTI, M.C., BUSE, M.G.: Administration of endotoxin, tumor necrosis factor, or interleukin I to rats activates skeletal muscle branched-chain a-keto acid dehydrogenase. J. Clin. Invest., 85, 256-263 (1990).

NELSON, M.E., FISHER, E.C., CATSOS, RD., MEREDITH, C.N., TURKSOY, R.N., EVANS, W.J.: Diet and bone status in amenorrheic runners. Am. J. Clin. Nutr., 43, 910-916 (1986).

NEWHAM, D.J., Mc PHAIL, G., MILLS, K.R., EDWARDS, R.H.T.: Ultrastructural changes after concentric and eccentric contractions of human muscle. J. Neurol. Sci., 61, 109-122 (1983).

O'REILLY, K.P., WARHOL, M.J., FIELDING, R.A., FRONTERA, W.R., MEREDITH, C.N., EVANS, W.J.: Eccentric exercise-induced muscle damage impairs muscle glycogen repletion. J. Appl. Physiol., 63, 252-256 (1987).

PEARSON, D.R., COSTILL, D.L.: The effects of constant external resistance exercise and isokinetic exercise training on work-induced hypertrophy. J. Appl. Sport Sci. Res., 2, 39-41 (1988).

RENNIE, M.J., HALLIDAY, D., DAVIES, C.T.M., EDWARDS, R.H.T., KRYWAWYCH, P.J., MILLWARD, P.J., MATTHEWS, D.E.: Exercise induced increase in leucine oxidation in man and the effect of glucose. In: Metabolism and Clinical Implications of Branched Chain Amino and Ketoacids, pp. 361-366, M. WALSER, D.H. WILLIAMSON (Eds.). Elsevier/North Holland, New York, NY, 1980.

RENNIE, M.J., EDWARDS, R.H.T., KRYWAWYCH, S., DAVIES, C., HALLIDAY, D., WATERLOW, J.C., MILLWARD, D.J.: Effect of exercise on protein turnover in man. Clin. Sci. Lond., 61, 627-639 (1981).

ROUND, J.M., JONES, D.A., CAMBRIDGE, G.: Cellular infiltrates in human skeletal muscle: exercise induced damage as a model for inflammatory muscle disease? J. Neurol. Sci., 82,1-11 (1987).

SANDIER, R.B.: Muscle strength assessment and the prevention of osteoporosis. J. Am. Geriat. Soc., 37, 1192-1197 (1989).

SMITH, J.K., GRISHAM, M.B., GRANGER, D.N., KORTHUIS, R.J.: Free radical defense mechanisms and neutrophil infiltration in postischemic skeletal muscle. Am. J. Physiol., 256, H789-H793 (1989).

TARNOPOLSKY, M.A., MacDOUGALL, J.D., ATKINSON, S.A.: Influence of protein intake and training status on nitrogen balance and lean body mass. J. Appl. Physiol, 64, 187-193 (1988).

TARNOPOLSKY, L.J., MacDOUGALL, J.D., ATKINSON, S.A., TARNOPOLSKY, M.A., SUTTON, J.R.: Gender differences in substrate for endurance exercise. J. Appl. Physiol., 68, 302-308 (1990).

TZANKOFF, S.P., NORRIS, A.H.: Longitudinal changes in basal metabolic rate in man. J. Appl. Physiol., 33, 536-539 (1978).

UAUY, R., SCRIMSHAW, N., YOUNG, V.: Human protein requirements: nitrogen balance response to graded levels of egg protein in elderly men and women. Am. J. Clin. Nutr., 31, 779-785 (1978).

VIHKO, V., SALMINEN, A., RANTAMAKI, J.: Exhaustive exercise endurance training, and acid hydrolase activity in skeletal muscle. J. Appl. Physiol., 47, 43-50 (1979).

VON LIEBIG, J.: Die Quelle der Muskelkraft. Ann. Chemie Pharmacie, 153, 157-228 (1870).

WARHOL, M.J., SIEGEL, A.J., EVANS, W.J., SILVERMAN, L.M.: Skeletal muscle injury and repair in marathon runners after competition. Am. J. Pathol., 118, 331-339 (1985).

YOUNG, V.: Amino acids and protein in relation to the nutrition of elderly people. Age Ageing, 19, 510-524 (1990).

ZANNI, E., CALLOWAY, D., ZEZULKA, A.: Protein requirements of elderly men. J. Nutr., 109, 513-524 (1979).