Common errors in diagnosis and management
The common errors in the diagnosis and management of severe
malaria are listed below.
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Errors in diagnosis Failure to think of malaria in a
patient with either typical or atypical illness Failure to elicit a history
of exposure (travel history) - including travel within a country with variable
transmission Misjudgement of severity Failure to do a thick blood film
in a non-immune patient Failure to identify P. falciparum in a dual
infection with P. vivax (the latter may be more obvious) Missed
hypoglycaemia Failure to diagnose other associated infections (bacterial,
viral, etc.) Misdiagnosis (e.g. influenza, viral encephalitis, hepatitis, scrub
typhus, etc.) Failure to recognize respiratory distress (metabolic acidosis)
Failure to carry out an ophthalmoscopic examination for the presence of
papilloedema, and retinal haemorrhages in adults. |
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Errors in management Inadequate nursing care (see page
10) Delay in starting antimalarial therapy Use of inappropriate therapy:
- chloroquine in areas of resistance - unjustified
withholding of an antimalarial drug - dosage not correctly calculated -
inappropriate route of administration (see inside front cover flap) -
unjustified cessation of treatment - failure to prevent cumulative effects
of antimalarial drugs - failure to switch patients from parenteral to oral
therapy as soon as they can take oral medication - unnecessary continuation
of chemotherapy beyond the recommended length of treatment (see inside front
cover flap) - use of unproven and potentially dangerous ancillary treatment
- failure to review antimalarial treatment in a patient whose condition is
deteriorating Errors of fluid and electrolyte replacement - failure to
control the rate of intravenous infusion
Failure to elicit a history of recent chemotherapy Failure
to identify or treat metabolic acidosis Unnecessary endotracheal intubation
Unduly delayed endotracheal intubation (where this is indicated and
possible) Failure to control convulsions Failure to recognize minor
(subtle) convulsions Failure to recognize and treat severe
anaemia Delay in considering obstetrical intervention in late pregnancy
Failure to recognize and manage pulmonary oedema Undue delay in starting
peritoneal dialysis or haemodialysis Failure to pass a nasogastric tube to
prevent aspiration pneumonia Failure to give antibiotics as a covering
procedure if the decision is made to delay lumbar puncture. |