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close this bookClinical Guidelines and Treatment Manual (Médecins Sans Frontières, 1993)
close this folderChapter 4 - Skin conditions
View the document(introductory text...)
View the documentDermatology
View the documentImpetigo and other purulent dermatoses
View the documentHerpes simplex, Herpes zoster
View the documentScabies
View the documentLeg ulcer
View the documentFungal infection
View the documentAnthrax
View the documentOther skin conditions
View the documentEndemic syphilis, Yaws & Pinta
View the documentLeprosy

Endemic syphilis, Yaws & Pinta

Non-venereal treponematoses, affecting bone, skin or mucosa and spread by direct contact. Their occurrence is associated with over crowding and poor hygiene.

Table 10

Treatment (dispensary)

- benzathine penicillin (IM)
Adult: 1.2 MIU in a single injection
Child: 600,000 IU in a single injection

- Note that syphilis (both primary and secondary) must be treated with double this dose of benzathine penicillin: 2.4 MIU IM stat.

- If allergic to penicillin: tetracycline or erythromycin (PO): 2 g/d or 50 mg/kg/d divided in 3 doses x 5 days (14 days for syphilis)


For all household contacts:
benzathine penicillin (IM)
Adult: 600,000 IU in a single injection
Child: 300,000 IU in a single injection