Magnesium
Magnesium is an essential mineral needed in relatively large
amounts by humans. In a number of retrospective studies magnesium levels during
pregnancy were found to be associated with the risk of seizures in
pre-eclampsia, prematurity and low birth weight (Ramakrisham et al. 1999, Makrides & Crowther 2000). This promising association has triggered a number
of controlled supplementation studies, which have been reviewed lately (Makrides & Crowther 2000). The authors of the Cochrane review concluded that there is
at present not enough evidence to show that dietary magnesium supplementation
during pregnancy is beneficial. No studies are available on magnesium
supplementation in developing countries, where the deficiency might be more
important.