Cost-Effectiveness Tool for Evaluating Interventions to Prevent Mother-to-Child Transmission - Manual and Model (UNAIDS, 2000, 94 p.): “TITLE” WORKSHEET

Cost-Effectiveness Tool for Evaluating Interventions to Prevent Mother-to-Child Transmission - Manual and Model (UNAIDS, 2000, 94 p.)

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INTRODUCTION

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PLEASE DO THIS FIRST

EXCEL VERSIONS OF THE CET AND “MACROS”

WHY THIS MANUAL?

OVERVIEW OF MANUAL

WORKING WITH THE CET

DOCUMENTING ESTIMATES

SOURCES OF DATA FOR CET INPUTS

ANALYTIC FEATURES OF THE CET

“TITLE” WORKSHEET

“SUMMARY” WORKSHEET

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SUMMARY TABLE -1: SELECTED INPUTS

SUMMARY TABLE -2: SELECTED HEALTH, COST AND COST-EFFECTIVENESS OUTCOMES

SUMMARY TABLE -3: INCREMENTAL COST-EFFECTIVENESS ANALYSIS

“SETTING” WORKSHEET

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TABLE SETTING-1: ANNUAL BIRTHS IN SERVICE AREA

TABLE SETTING-2: BIRTHS REACHABLE BY INTERVENTIONS

TABLE SETTING-3: PERCENT ARRIVING AT CLINIC IN EACH GESTATIONAL AGE INTERVAL.

TABLE SETTING-4: HIV PREVALENCE RATE IN PREGNANT WOMEN

TABLE SETTING-5: RATE OF PERINATAL MOTHER-TO-CHILD HIV TRANSMISSION

TABLE SETTING-6: DISCOUNT RATE

TABLE SETTING-8: LIFE EXPECTANCY

“INTERVENTIONS” WORKSHEET

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TABLE INTERVENTION - 1: SPECIFYING INTERVENTIONS

“VCT” WORKSHEET

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TABLE VCT-1: PER-CLIENT COST OF VCT

TABLE VCT-2: “EXTERNAL” COST OF VCT

TABLE VCT-3: SUMMARY VCT INFORMATION

TABLE VCT-4: DETAILED VCT INFORMATION (VARIABLE COSTS)

TABLE VCT- 5: DETAILED VCT INFORMATION: (FIXED COSTS EXCLUDING CAPITAL COSTS)

TABLE VCT-6: DETAILED VCT INFORMATION: CAPITAL COSTS

TABLE VCT-7: VARIABLE COST OF VCT BY TASK

“ARV” WORKSHEET

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TABLE ARV-1: REGIMEN COMPONENTS

TABLE ARV-2: GESTATIONAL AGE AT START OF TREATMENT

TABLE ARV-3: MOTHERS AND CHILDREN RECEIVING VARIOUS SERVICE COMPONENTS

TABLE ARV-4: DOSES, DRUGS AND DRUG COSTS.

TABLE ARV-5: EFFECTIVENESS ESTIMATES

TABLE ARV-6: ARV EFFECTIVENESS - ADJUSTMENTS FOR IMPERFECT ADHERENCE

“SUBSTITUTE FEEDING” WORKSHEET

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TABLE SF - 1: DURATION OF BREASTFEEDING AND SUBSTITUTE FEEDING

TABLE SF - 2: BREASTFEEDING, HIV RISK, AND NON-HIV MORTALITY

TABLE SF - 3: HEALTH OUTCOMES (PER 100 CHILDREN OF HIV+ MOTHERS)

TABLE SF - 4: PROGRAM COSTS - COUNSELING, TRAINING AND SUBSTITUTE FOOD

TABLE SF - 5: HIV AND NON-HIV MEDICAL COSTS

TABLE SF - 6: SUMMARY OF SUBSTITUTE FEEDING COST OUTCOMES

“COST OF HIV/AIDS” WORKSHEET

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TABLE COST OF HIV/AIDS - 1: SUMMARY INFORMATION

TABLE COST OF HIV/AIDS - 2: DETAILED INFORMATION

“RESULTS” WORKSHEET

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TABLE RESULTS - 1: HEALTH, COST AND COST-EFFECTIVENESS RESULTS

TABLE RESULTS - 2: EXPLORING THE RESULTS

TABLE RESULTS - 3: INCREMENTAL COST-EFFECTIVENESS

“SENSITIVITY ANALYSES (SAs)” WORKSHEET

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SENSITIVITY ANALYSIS GRAPHS: COST PER DALY AS A FUNCTION OF FOUR KEY VARIABLES

TABLE SA-1: UNI-VARIABLE SENSITIVITY ANALYSES

TABLE SA-2: MULTI-VARIABLE SENSITIVITY ANALYSES

“DALY CALCULATION” WORKSHEET

PUBLISHED STUDIES AND OTHER RESOURCES

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SETTING

VOLUNTARY COUNSELING AND TESTING (VCT)

ARVs

SUBSTITUTE FEEDING

COST OF HIV/AIDS

SENSITIVITY ANALYSIS

DALY CALCULATIONS

APPENDIX A: DATA INPUTS DOCUMENTATION TABLE

Cost-Effectiveness Tool for Evaluating Interventions to Prevent Mother-to-Child Transmission - Model

“TITLE” WORKSHEET

This worksheet provides contact information for assistance, and the current version number of the CET. We believe it is self-explanatory.

No data entry is required on this worksheet.