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close this bookNew Data on the Prevention of Mother-to-Child Transmission of HIV and Their Policy Implications (UNAIDS, 2001, 24 p.)
close this folderConclusions and recommendations regarding infant feeding
View the documentRisks of breastfeeding and replacement feeding
View the documentCessation of breastfeeding
View the documentInfant feeding counselling
View the documentBreast health
View the documentMaternal health

Maternal health

In one trial, the risk of dying in the first 2 years after delivery was greater among HIV-infected women who were randomized to breastfeeding than among those who were randomized to formula feeding.54 This result has yet to be confirmed by other research.

Women who do not breastfeed or stop breastfeeding early are at greater risk of becoming pregnant.

Recommendation: HIV-infected women should have access to information, follow-up clinical care and support, including family planning services and nutritional support. Family planning services are particularly important for HIV-infected women who are not breastfeeding.

Regimens of proven efficacy (randomized controlled clinical trials)


Antepartum

Intrapartum

Postpartum/postnatal

Study

Drug

14-28 wks

28-36 wks

>36 wks

Labour

1 wk PP

1-6 wks PP

ACTG 076

ZDV



Infant

Harvard Thai

ZDV




Infant

Harvard Thai

ZDV




Infant


Harvard Thai

ZDV




Infant

Harvard Thai

ZDV




Infant


DITRAME

ZDV




Mother


CDC

ZDV





PETRA Arm A

ZDV + 3TC




Mother and Infant


PETRA Arm B

ZDV + 3TC



Mother and Infant


HIVNET/SAINT

NVP



Infant