UNAIDS-Sponsored Regional Workshops to Discuss Ethical Issues in Preventive HIV Vaccine Trials (UNAIDS, 2000, 52 p.): WORKSHOP REPORTS: ENTEBBE, UGANDA, 27-29 APRIL, 1998: 11. Children

UNAIDS-Sponsored Regional Workshops to Discuss Ethical Issues in Preventive HIV Vaccine Trials (UNAIDS, 2000, 52 p.)

WORKSHOP REPORTS

ENTEBBE, UGANDA, 27-29 APRIL, 1998

		1. Phase I/II (Safety and Immunogenicity) Trials
		2. Phase III Trials
		3. Vulnerability to Harm and Exploitation
		4. Community
		5. Ethical Review
		6. Intellectual Property
		7. Control Arm in Trials
		8. Informed Consent
		9. Counselling
		10. Gender, Pregnancy and Breast-Feeding
		11. Children
		12. Discrimination
		13. Treatment and Care
		14. Endpoints in Vaccine Trials
		15. Compensation for Injury or Harm
		16. Access and Availability of Vaccine

11. Children

Discussion:

The group recognized the importance of children and adolescents in HIV vaccine trials, but was unable to adequately discuss the issue due to time constraints. One group proposed that children of mothers who received the candidate vaccine should be enrolled in the trial for collection of data only, but that children should not generally be enrolled in a trial until following successful completion of a phase III trial in adults. This is because they cannot give adequate informed consent. However, the ages at which childhood effectively begins and ends was not defined.