(introduction...)
Mother-to-child transmission (MTCT) of HIV, which can occur
during pregnancy, delivery or breastfeeding, is responsible for more than 90% of
HIV infection in children worldwide (UNAIDS/WHO, 1998). The present
review focuses on HIV-1. Both HIV type 1 (HIV-1) and HIV type 2 (HIV-2) can be
transmitted from mother to child, but HIV-2 is transmitted much less frequently,
as it is less pathogenic than HIV-1 (Adjorlolo-Johnson et al., 1994;
Andreasson et al., 1993; Morgan et al., 1990).
The remaining 10% of paediatric infections are attributed to
transfusion with contaminated blood and blood products, use of contaminated
medical equipment, other practices that cut or pierce the skin, or sexual
contact (MAP, 1998; UNAIDS/WHO, 1998; Tovo et al.,
1988).